Functional MRI Motor Imagery Tasks to Detect Command Following in Traumatic Disorders of Consciousness

Functional MRI Motor Imagery Tasks to Detect Command Following in Traumatic Disorders of Consciousness

Severe traumatic brain injury impairs arousal and awareness, the two components of consciousness. Accurate diagnosis of a patient's level of consciousness is critical for determining treatment goals, access to rehabilitative services, and prognosis. The bedside behavioral examination, the current clinical standard for diagnosis of disorders of consciousness, is prone to misdiagnosis, a finding ...

An f MRI Study of Command Following and Communication Using Overt and Covert Motor Responses: Implications for Disorders of Consciousness

Spatio-Temporal Decorrelated Activity Patterns in Functional MRI Data during Real and Imagery Motor Tasks

We present a new method for separating multiple task-related events and other physiological and physical events revealed by functional MRI (fMRI) signals. Each event is a three-dimensional spatial pattern of brain activation and an associated timecourse. The method separates fMRI signals into di erent events by minimizing the spatial and temporal correlations between events. We derived a closed...

Electromyographic decoding of response to command in disorders of consciousness.

OBJECTIVE To propose a new methodology based on single-trial analysis for detecting residual response to command with EMG in patients with disorders of consciousness (DOC), overcoming the issue of trial dependency and decreasing the influence of a patient's fluctuation of vigilance or arousal over time on diagnostic accuracy. METHODS Forty-five patients with DOC (18 with vegetative/unresponsi...

Functional MRI in disorders of consciousness: advantages and limitations.

PURPOSE OF REVIEW We discuss recent developments in the use of neuroimaging and, in particular, functional MRI, in the assessment of patients diagnosed as vegetative state or minimally conscious state. RECENT FINDINGS In the last year, there has been a substantial increase in the number of research studies published which have used state-of-the-art neuroimaging methods to assess residual cogn...